Table 5.
Genotype and Allele Frequencies Distribution in Different Grades of CRC a
| High Grade No. (%) | Low Grade No. (%) | OR | CI 95% | Adjusted ORb | CI 95% c | Adjusted | |||
|---|---|---|---|---|---|---|---|---|---|
| Allele | |||||||||
| A | 21 (66) | 114 (44) | 2.445 | 1.133 | 5.278 | 2.437 | 1.127 | 5.268 | 0.024 |
| G | 11 (34) | 146 (56) | Ref | Ref | |||||
| Genotype | |||||||||
| AA | 8 (50) | 27 (20.8) | 4.247 | 1.035 | 17.421 | 4.283 | 1.039 | 17.648 | 0.044 |
| GA | 5 (31.3) | 60 (46.2) | 1.194 | 0.271 | 5.268 | 1.23 | 0.277 | 5.465 | 0.785 |
| GG | 3 (18.8) | 43 (33.1) | Ref. | Ref. | |||||
| Recessive Model | AA vs. GA+GG | 3.815 | 1.312 | 11.096 | 3.781 | 1.296 | 11.029 | 0.015 | |
| Dominant Model | GG vs. GA+AA | 0.467 | 0.126 | 1.726 | 2.203 | 0.592 | 8.202 | 0.239 | |
aHigh grade patients (poor) were compared with low grades patients (well and moderately). bAR, Adjusted for Age and Sex; cCI, confidence interval.