Table 4.
Descriptive analysis of the response rate, PASI, adverse reactions (comparing ex-CHM with other therapies for psoriasis vulgaris treatment)
| Study | Sample size (E/C) | Intervention (E/C) |
Response rate | PASI | Adverse dermatological reactions | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
RR (95% CI) |
P value |
MD
(95% CI) |
P value |
RR
(95% CI) |
P value |
||||||||||||
| Zhang 201525 | 29/29 | CHM ointment/tretinoin cream | 1.40 (0.50, 3.90) |
0.52 | －0.23 (－1.34, 0.88) |
0.69 | 0.20 (0.01, 3.99) |
0.29 | |||||||||
| Chen 201626 | 60/60 | CHM ointment+acitretin /acitretin |
1.02 (0.88, 1.18) |
0.79 | 0.28 (0.13, 0.60) |
0.001 | |||||||||||
| Wang et al 201930 |
46/41 | CHM external washing/calcipotriol ointment | 1.01 (0.79, 1.28) |
0.96 | －0.14 (－1.32, 1.04) |
0.82 | 0.13 (0.01, 2.40) |
0.17 | |||||||||
| Jiang 201728 | 30/30 | CHM external washing+ exhormone /ex-hormone |
1.39 (1.00, 1.94) |
0.05 | －2.00 (－2.93, －1.07) |
<0.0001 | 0.20 (0.01, 4.00) |
0.29 | |||||||||
| Wei et al 201524 |
64/64 | CHM fumigation combined with external washing+ acitretin/acitretin | 1.26 (1.02, 1.56) |
0.03 | －2.95 (－4.25, －1.65) |
<0.000 01 | 2.00 (0.38, 10.54) |
0.41 | |||||||||
| Lin et al 202031 | 40/40 | CHM fumigation+calcipotriol ointment /calci-potriol ointment |
5.00 (2.13, 1.75) |
0.0002 | －2.88 (－3.13, －2.63) |
<0.000 01 | 0.20 (0.05, 0.86) |
0.03 | |||||||||
| Su et al 201523 | 42/43 | CHM bath+308 nm excimer laser/308 nm excimer laser | 1.18 (0.96, 1.46) |
0.11 | －4.28 (－6.12, －2.44) |
<0.000 01 | 0.26 (0.08, 0.84) |
0.02 | |||||||||
Notes: CHM: Chinese Herbal Medicine; ex-CHM: external application of CHM; Ex-hormone: external application of hormone; PASI: psoriasis area and severity index; RR: risk ratio; MD: mean difference; CI: confidence interval; E: the experiment group; C: the control group.