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. 2023 Feb 15;43(1):124–133. doi: 10.19852/j.cnki.jtcm.2023.01.011

Figure 4. HE images revealing mucosal integrity in tissues in 10 d.

Figure 4

A, H: mucosal integrity in tissues (× 100 and × 200) of control group treating saline treatment control for 10 d. B, E: mucosal integrity in tissues (×100 and ×200) of DSS group consuming 2.5% DSS water for 7 d followed by an additional consumption period of normal drinking water for 3 d. C, G: mucosal integrity in tissues (× 100 and × 200) of (5-ASA+DSS) group fed with 2.5% DSS, and respectively given with 5-ASA o.g.; 100 mg·kg-1·d-1) from day 0 till the end of experiment for a total of 10 d. D, H: mucosal integrity in tissues (× 100 and × 200) of (QD + DSS) group fed with 2.5% DSS, and respectively given with QD (o.g.; 1.3 g raw herbs·kg-1·d-1) from day 0 till the end of experiment for a total of 10 d. I: Histological scores were given based on the severity of colonic damages, lymphocyte infiltration and crypt disruption (n = 8/group). HE: hematoxylin-eosin; QD: Qingdai (Indigo Naturalis); DSS: dextran sodium sulfate; 5-ASA: 5-aminosalicylic acid. aP < 0.005 DSS group compared with Control groups; bP < 0.05, (5-ASA + DSS) group compared with DSS groups; cP < 0.05, (QD + DSS) group compared with DSS groups.