Table 2.
Comparison of baseline perioperative and donor data between patients undergoing liver transplantation assigned to 28% and 80% postoperative FiO2
| Variables | 28% FiO2 (n = 99) | 80% FiO2 (n = 94) | p |
|---|---|---|---|
| Retransplantation | 2 (2.0%) | 4 (4.3%) | .435 |
| Caval anastomosis: | .675 | ||
| Piggyback | 87 (87.9%) | 80 (85.1%) | |
| Conventional | 12 (12.1%) | 14 (14.9%) | |
| Veno-venous bypass | 17 (17.2%) | 16 (17.0%) | > .999 |
| Biliary anastomosis | .692 | ||
| Duct-to-duct | 85 (85.9%) | 78 (83.0%) | |
| Hepaticojejunostomy | 14 (14.1%) | 16 (17.0%) | |
| Operative time (minutes) | 370 (330–420) | 363 (330–430) | .591 |
| Extubation | .450 | ||
| Early | 84 (84.8%) | 75 (79.8%) | |
| Late | 15 (15.2%) | 19 (20.2%) | |
| Cold ischemic time (minutes) | 480 (422–558) | 480 (415–535) | .439 |
| Warm ischemic time (minutes) | 50 (42–64) | 53 (45–64) | .337 |
| Intraoperative PRBC transfusions (units) | 3 (0–6) | 4 (1–7) | .294 |
| Intraoperative FFP transfusions (units) | 4 (0–6) | 4 (2–7) | .070 |
| Intraoperative dialysis | 3 (3.0%) | 4 (4.3%) | .715 |
| Donor age (years) | 49 (37–58) | 48 (38–59) | .966 |
| Male donor sex | 62 (62.6%) | 55 (58.5%) | .659 |
| Immunosuppressive treatment: | |||
| Steroids | 99 (100%) | 94 (100%) | - |
| Tacrolimus | 97 (98.0%) | 90 (95.7%) | .435 |
| Mycophenolate mofetil | 49 (49.5%) | 45 (47.9%) | .886 |
| Basiliximab | 72 (72.7%) | 67 (71.3%) | .873 |
| Laboratory parameters after intervention | |||
| PaO2 (mmHg) | 103 (89–122) | 311 (255–364) | < .001 |
| PaCO2 (mmHg) | 41 (36–46) | 41 (36–46) | .933 |
| pH | 7.38 (7.33–7.41) | 7.36 (7.33–7.41) | .470 |
| Oxygen saturation (%) | 98.6 (97.5–99.0) | 99.7 (99.5–99.9) | < .001 |
| Lactate concentration (mmol/L) | 1.8 (1.1–2.7) | 1.9 (1.4–2.6) | .217 |
Data are presented as n (%) or median (interquartile range)
FiO2 Fraction of inspired oxygen, PRBC Packed red blood cells, FFP Fresh frozen plasma, PaO2 Arterial partial oxygen pressure, PaCO2 Arterial partial carbon dioxide pressure