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. 2023 Feb 13;8:13. doi: 10.1038/s41541-023-00612-2

Fig. 1. AS03-adjuvanted CoVLP triggers robust antibody response to wild-type SARS-CoV-2 antigens across different vaccine doses.

Fig. 1

a The dot plots show the univariate comparisons of WT Spike-specific IgG1, IgG2, IgG3, IgG4, IgM, and IgA across the vaccinees that received different doses (3.75, 7.5, and 15 µg) of CoVLP without AS03 (shades of blue, n = 16) and CoVLP with AS03 (shades of yellow, n = 17) and at days 42 and 201. Lines connect the median values of groups. b A principal component analysis (PCA) was applied to all samples and data to examine the impact of vaccine dose with and without AS03 adjuvant (different shades of blue and orange) and time since vaccination (day 42 in circles and day 201 in triangles).