Table 2.
Clinical data of the control group.
| ID | Age | Sex | Hospitalization (days) | Hypertension | PMI | Antemortem head CT | Neurological signs | Neuropathological evaluation | Brainstem hypoxic damage | Microthrombosis (NON-CNS) | Cause of death |
|---|---|---|---|---|---|---|---|---|---|---|---|
| #1 | 83 | M | 10 | Y | 5 | Cerebral atrophy, Chronic ischemic vascular disease | Cognitive decline | Mixed dementia with AD neuropathological changes ad chronic ischemic vascular disease | Moderate | No | Pneumonia, respiratory insufficiency, ischemic heart disease |
| #2 | 74 | M | 2 | Y | 4 | Vascular calcification, ischemic heart disease | NA | Chronic ischemic vascular disease | Mild | No | Ischemic heart disease |
| #3 | 40 | M | 1 | N | 4 | No signs | No signs | No detectable microscopical changes | No detectable microscopical changes | No | Haemorrhagic Shock |
| #4 | 79 | F | 31 | Y | 3 | Cerebral atrophy, Chronic ischemic vascular disease | Cognitive decline, Alzheimer type | AD neuropathological changes, CAA, ischemic vascular disease | Mild | No | Pentalobar pneumonia, respiratory insufficiency |
| #5 | 62 | M | 22 | Y | 5 | NA | NA | Diffuse hypoxic/ischemic damage | Mild | No | Pneumonia, respiratory insufficiency |
| #6 | 76 | M | 15 | Y | 6 | NA | NA | Ischemic vascular disease, diffuse hypoxic/ischemic damage | Mild | No | Pneumonia, chronic ischemic vascular disease |
| #7 | 75 | M | 12 | Y | 4 | NA | NA | Diffuse hypoxic/ischemic damage | Mild | No | Pneumonia, ischemic heart disease |
| #8 | 78 | F | 8 | Y | 3 | No | NA | Diffuse hypoxic/ischemic damage | Mild | No | Pneumonia, ischemic heart disease |
| #9 | 71 | F | 40 | Y | 3 | NA | NA | Diffuse hypoxic/ischemic damage | Moderate to severe | No | Acute respiratory failure, septic shock, peritonitis |
| #10 | 46 | F | 15 | N | 4 | No signs | No signs | Diffuse hypoxic/ischemic damage | No detectable microscopical changes | No | Respiratory insufficiency, multiorgan failure, cervical neoplasia |
| #11 | 75 | F | 20 | Y | 5 | Chronic Ischemic Vascular disease, Cerebral atrophy | NA | Vascular dementia, ischemic vascular disease, diffuse hypoxic/ischemic damage | Moderate | No | Pneumonia, acute respiratory failure, candidosis |
| #12 | 80 | F | 8 | Y | 4 | Cerebral atrophy | Cognitive decline, Alzheimer type | AD neuropathological changes, diffuse hypoxic/ischemic damage | Moderate | No | Pentalobar pneumonia, respiratory insufficiency |
| #13 | 81 | F | NA | Y | 3 | NA | NA | Diffuse hypoxic/ischemic damage | Mild | No | Pneumonia, acute respiratory failure |
| #14 | 63 | F | NA | N | 3 | No signs | No signs | Diffuse hypoxic/ischemic damage | Mild | No | Ischemic heart disease |
| #15 | 70 | M | 38 | Y | 5 | Chronic ischemic vascular disease | NA | Ischemic vascular disease, diffuse hypoxic/ischemic damage | Moderate | No | Bilateral pneumonia, respiratory insufficiency |
| #16 | 81 | M | 10 | Y | 4 | Cerebral atrophy | Cognitive decline, Alzheimer type | Mixed AD neuropathological changes and Lewy Body pathology, diffuse hypoxic/ischemic damage | Moderate | No | Pneumonia, respiratory insufficiency |
| #17 | 75 | M | 58 | Y | 6 | Cerebral atrophy | NA | Vascular dementia, ischemic vascular disease, diffuse hypoxic/ischemic damage | Moderate | No | Pneumonia, respiratory insufficiency |
| #18 | 87 | M | 30 | Y | 6 | Cerebral atrophy | Cognitive decline | AD neuropathological changes, diffuse hypoxic/ischemic damage | Moderate | No | Pneumonia, multiorgan failure |