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STAT3 regulates the levels of DNMT3B in human chondrocytes. (a) STAT3 knock down in fetal chondrocyte leads to transcriptional activation of DNMT3B. (b) Pharmacological activation of STAT3 in adult chondrocyte leads to transcriptional repression of DNMT3B. Statistical analysis was performed using two‐tailed Student's t test in GraphPad prism 9.0 and p < 0.05 was considered as statistically significant. Mean with standard deviation is plotted.
