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. 2023 Feb 13;18(2):e0281735. doi: 10.1371/journal.pone.0281735

Fig 6. Tumor suppression and percent survival of mice engrafted with Raji cells and treated with CAR-CD19 T cells.

Fig 6

Tumor burden in immunocompromised mice engrafted with Raji expressing luciferase as assessed by bioluminescence following treatment with the indicated doses of CAR-CD19 T cells. (A) Normalized bioluminescence intensity was shown are the mean ± SEM. (B) Percent survival of C.B.17/Icr-scid/scidJcl mice engrafted with 5 x 105 Raji cells two weeks before administration of the indicated dose of CAR-CD19 T cells. Note: mice in control groups had been culled due to disease progression prior to week 4. N ≥ 4 mice/group.