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a. Study flow for stage 1. b. Stage 2 cohorts. FCZ = fluconazole; AMB = amphotericin B; DLT = dose limiting toxicity; MTD = maximum tolerated dose; SMC = safety monitoring committee. Participants from Stage 1 for each of the 1600mg and 2000mg FCZ and AMB cohorts were combined with the participants from the Stage 2 group for the final safety and efficacy analysis.
