Table 1.
Comparison of continuous glucose monitoring systems
| Dexcom G6 | Dexcom G7 | Guardian Sensor 3 | Guardian Sensor 4 | FreeStyle Libre | FreeStyle Libre 2 | FreeStyle Libre 3 | Eversense | Eversense E3 | |
|---|---|---|---|---|---|---|---|---|---|
| Company | Dexcom | Dexcom | Medtronic | Medtronic | Abbott | Abbott | Abbott | Senseonics | Senseonics |
| Size, mm | 45×30×15 | 27.3×24×4.6 | 35×28×9.5 | 35×28×9.5 | 35×5 | 35×5 | 21×2.9 | 18.3×3a | 18.3×3a |
| FDA approved year | 2018 | Awaiting | 2018 | Awaiting | 2017 | 2020 | 2022 | 2018 | 2022 |
| Approved age | ≥2 years | ≥2 years | ≥2 years | ≥14 years | ≥18 years | ≥4 years | ≥4 years | ≥18 years | ≥18 years |
| Sensor type | Real-time | Real-time | Real-time | Real-time | Intermittent scanning | Intermittent scanning | Real-time | Real-time (implantable) | Real-time (implantable) |
| Wear time | 10 days | 10.5 days | 7 days | 7 days | 14 days | 14 days | 14 days | 90 days | 180 days |
| Warm-up period | 2 hours | 27 minutes | 2 hours | 2 hours | 1 hour | 1 hour | 1 hour | 24 hours | 24 hours |
| Calibration required | No | No | Yes (2 times/day) | No | No | No | No | Yes (2 times/day) | Yes (2 times/day for 21 days, 1 time/day after day 21) |
| Alarms for hypo/hyperglycemia | Yes | Yes (can be delayed up to 6 hours) | Yes | Yes | No | Yes (optional) | Yes (optional) | Yes (on-body vibration) | Yes (on-body vibration) |
| Integrity with insulin pumps | Yes | Yes | Yes | Yes | No | Yes | Yes | No | No |
| Platform | Dexcom clarity | Dexcom clarity | CareLink Personal | CareLink Personal | Libreview | Libreview | Libreview | ||
| LibreLinkUp | Eversense DMS | Eversense DMS | |||||||
| Accuracy (MARD) | 10.0% | 8.2% (arm), 9.1% (abdomen) | 8.7% (arm), 9.6% (abdomen) | 10.6% | 11.4% (arm) | 9.2% (adults), 9.7% (pediatrics) | 9.2% (adults), 9.7% (pediatrics) | 8.8% | 9.1% |
| Accuracy in low glucose range (MAD) | 10.9 mg/dL (glucose level <54 mg/dL) | 8.5 mg/dL (arm), 10.3 mg/dL (abdomen) (glucose level 40–60 mg/dL) | NA | NA | 11.3 mg/dL (glucose level <100 mg/dL) | 9.1 mg/dL (adults), 8.8 mg/dL (pediatrics) | 9.1 mg/dL (adults), 8.8 mg/dL (pediatrics) | NA | 7.5 mg/dL (glucose level ≤60 mg/dL) |
| Bluetooth free range | 6 m | 6 m | 6 m | 6 m | NA | NA | 10 m | 7.6 m | 7.6 m |
FDA, U.S. Food and Drug Administration; MARD, mean absolute relative difference; MAD, mean absolute difference; NA, not applicable.
a
Implantable sensor size.