Table 2.
List of Saliva-based microfluidic devices reported in the literature. Also given is assay type, specific biomarker, and associated illness.
| Platform | Assay Type | Analyte | Associated Illness | Source |
|---|---|---|---|---|
| LFA | Colorimetric | Cortisol | Adrenal gland disorders | 138 |
| LFA | Colorimetric | Cortisol | Adrenal gland disorders | 139 |
| LFA | Fluorescence | Extracellular vesicles | 140 | |
| LFA | Colorimetric | Cocaine | Substance Dependence | 114 |
| LFA | Colorimetric | Morphine and methamphetamine | Substance Dependence | 115 |
| LOC | Fluorescence | Cotinine | Tobacco smoke exposure | 119 |
| LOC | CARD | Viral RNA and anti-HIV antibodies | HIV | 141 |
| LOC | Fluorescence | Viral RNA | ZIKA | 142 |
| LOC | Colorimetric | ZIKA virus | ZIKA | 123, 143 |
| LOC | Electrochemical | Prostate-Specific Antigen | Prostate Cancer | 124 |
| LOC | Colorimetric | Anti-p53 autoantibodies | Oral Cancer | 125 |
| LOC | Absorbance | IL-8, IL-1β (proteins) | Cancer, arthritis, and cardiovascular disease | 92 |
| µPAD | Colorimetric | Glucose | Diabetes | 126 |
| µPAD | Electrochemical | Glucose | Diabetes | 128 |
| µPAD | Colorimetric | Nitrite and nitrate | Oral diseases | 127 |
| µPAD | Colorimetric | Thiocyanate | Tobacco smoke exposure | 144 |
| µPAD | Electrochemical | Cholesterol | Heart disease | 129 |
| µPAD | Electrochemical | Tetrahydrocannabinol (THC) | Substance Dependence | 131 |
| µPAD | Colorimetric and electrochemical | Influenza virus | Flu | 133 |