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. 2022 Dec 20;55(2):333–345. doi: 10.1038/s41588-022-01260-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 9 — (a–c) UMAP of the combined sortChIC data with the position of a selection of FACS sorted cells highlighted. neutrophils, monocytes, and DCs are labeled in (a) pDCs in (b) and B and NK cells in (c). (d) Schematic illustrating how reference cell types are used to systematically assign the rest of the cells without FACS-defined cell type label. (e) Final UMAP of the bone marrow data across four histone marks after assigning cell types to one of the 14 cell types in the reference.