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. 2023 Jan 24;40(2):117–134. doi: 10.1007/s40266-022-01001-5

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 2 — Forest plot showing the proportion [95% confidence interval (CI)] of older (aged ≥ 65 years) community-dwelling individuals potentially exposed to a drug–drug interaction (DDI)^*‡, identified using the 2015 American Geriatrics Society Beers criteria^®. n, numerator (number aged ≥65 years with a DDI ); N, denominator (sample size, aged ≥ 65 years). ^*Denominator (N): total number of participants aged ≥ 65 years included in the study; ^‡DDI classification: “Potentially Clinically Important Non-Anti-infective Drug–Drug Interactions That Should Be Avoided in Older Adults”.