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. 2023 Feb 1;15:200255. doi: 10.1016/j.tvr.2023.200255

Table 3.

Standardised rate ratios based on age-standardised prevalence rates comparing pre- and post-vaccination LA estimates and post-vaccination estimates between LA, cobas and other monitoring strategies.

HPV type Standardised Rate Ratios
LA (post-vaccination) vs. WHINURS LA (pre-vaccination) (95%CI) cobas vs. LA (95%CI) cobas/LA vs. LA (95%CI) Alg. A vs LA (95%CI) Alg. B vs. LA (95%CI)
HPV16 0.33 (0.21–0.52) 0.83 (0.50–1.34) 0.95 (0.59–1.53) 1.15 (0.73–1.83) 0.79 (0.48–1.31)
HPV16/18 0.34 (0.23–0.59) 0.90 (0.60–1.34) 0.98 (0.66–1.45) 1.17 (0.81–1.71) 0.80 (0.53–1.21)
Non-16/18 HPV types 0.68 (0.55–0.84) 0.94 (0.79–1.13) 0.93 (0.77–1.11) 1.14 (0.96–1.35) 0.79 (0.65–0.96)
HPV types in 9V vaccine (16,18, 31, 33, 45, 52, 58) Not applicable* Not applicable * 0.88 (0.70–1.10) Not applicable * 0.60 (0.47–0.77)
Non-16/18 HPV in 9V vaccine (31,33, 45,52,58) Not applicable* Not applicable * 0.83 (0.62–1.11) Not applicable * 0.84 (0.63–1.12)
All oncogenic HPV 0.58 (0.48–0.69) 0.93 (0.79–1.10) 0.93 (0.79–1.10) 1.14 (0.98–1.34) 0.79 (0.67–0.94)

*Prevalence for HPV types included in the nonavalent vaccine could not be determined as positivity for non-16/18 HPV positive samples is pooled and cannot distinguish between individual HPV types for cobas; similarly, results provided by WHINURS for non-16/18 types were pooled.