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. 2023 Feb 13;14:797. doi: 10.1038/s41467-023-36296-4

Fig. 4. Charting the T/NK landscape in the PDAC tumor microenvironment.

Fig. 4

A UMAP overview of the T/NK compartment. NK natural killer, UMAP uniform manifold approximation and projection. B The most differentially expressed gene within each T/NK cluster. C UMAP of the more granular CD8 + T cell reclustering reveals additional subpopulations. D The most differentially expressed gene within each CD8 + T cell cluster. E Hierarchical clustering of the CD8 + T cell subsets based on dysfunction and cytotoxicity scores. F Composition of the CD8 + T cell subset (excluding the two non-T cell clusters and the single-patient cluster).