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. 2023 Feb 13;14:797. doi: 10.1038/s41467-023-36296-4

Fig. 6. Chemotherapy treatment induces transcriptional changes in cancer cells independent of subtype.

Fig. 6

A Basal and classical signature expression scatterplot of cancer cells (treated, naive and combined). B Basal and classical signature expression scatterplot of cancer cells (treated and naïve by patient, combined by treatment); sample P03 has been removed from the combined plot. C Box plot showing the median intracluster correlation of cancer cells by sample for treated (n = 6) and naive (n = 11) groups (two-sided Wilcoxon rank-sum test, p = 0.26; box plots centered around the median with hinges at 1st and 3rd quartiles and whiskers from hinge to max value or 1.5*IQR, whichever is smallest). D Density plots of cancer cell correlation within samples for treated and untreated groups. E Gene set enrichment analysis of overall cancer cells, treated and untreated.