Roles of miR-200 family members in brain metastases from lung cancer, breast cancer, melanoma and gastrointestinal cancer. Parts of the figure were drawn using images from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). VEGF, endothelial growth factor; KDR, kinase insert domain receptor; Flt1, FMS-like tyrosine kinase; HIF-1α, hypoxia-inducible factor-1α; EMT, epithelial-to-mesenchymal transition; ZEB1, zinc finger E-box-binding homeobox-1; ZEB2, zinc finger E-box-binding homeobox-2; SIP1, smad interacting protein-1; IL-8, interleukin-8; CXCL1, chemokine (C-X-C motif) ligand-1; ADAM12, a disintegrin and metalloproteinase domain-containing protein-12; FAP-1, Fas-associated phosphatase 1; MARCKS, myristoylated alanine-rich C-kinase substrate; SP-1, specificity protein 1; KRAS, Kirsten rat sarcoma virus; FOXC1, forkhead box C-1; TGFB, transforming growth factor-B.