TABLE 2.
Summary data on rate ratios for unintentional traumatic injury after time‐varying covariate adjustment and semi‐Bayes shrinkage, by antidepressant
| Antidepressant a | Number of triads examined | Range of RRs, min – max | Number (%) of triads with statistically elevatedRRs b , c |
|---|---|---|---|
| Amitriptyline | 6979 | 0.31 – 2.36 | 6 (0.1) |
| Bupropion | 8062 | 0.28–2.07 | 7 (0.1) |
| Citalopram | 13,833 | 0.33–2.94 | 69 (0.5) |
| Desipramine | 5 | 0.39–0.54 | 0 |
| Desvenlafaxine | 620 | 0.49–2.23 | 0 |
| Doxepin | 1012 | 0.41–1.78 | 0 |
| Duloxetine | 13,258 | 0.32–2.63 | 20 (0.2) |
| Escitalopram | 14,562 | 0.39–6.60 | 66 (0.5) |
| Fluoxetine | 9324 | 0.38–2.74 | 13 (0.1) |
| Fluvoxamine | 3 | 0.25–0.32 | 0 (0.0) |
| Imipramine | 91 | 0.65–2.38 | 0 (0.0) |
| Mirtazapine | 8190 | 0.41–2.92 | 19 (0.2) |
| Nortriptyline | 2031 | 0.46–1.92 | 0 (0.0) |
| Paroxetine | 7100 | 0.33–2.31 | 20 (0.3) |
| Sertraline | 15,847 | 0.29–2.84 | 80 (0.5) |
| Trazodone | 12,262 | 0.38–2.51 | 28 (0.2) |
| Venlafaxine | 7262 | 0.41–2.16 | 6 (0.1) |
| Vilazodone | 72 | 0.88–2.31 | 0 |
| Vortioxetine | 201 | 0.60–1.67 | 0 |
Abbreviation: RR, rate ratio.
a
Brexpiprazole, clomipramine, and nefazodone were examined but did not have valid models and thus were excluded from this table.
b
After semi‐Bayes shrinkage.
c
Proportion was calculated for each antidepressant as the number of triads with statistically elevated RRs divided by the number of triads examined. For example, sertraline had 80 triads with statistically elevated RRs out of 15,847 triads examined, therefore the proportion was calculated as 80/15,847 = 0.5%.