Fig. 6.

Relationship between General Distress and connectivity in both the VS-mOFC and VS-amygdala circuits during reward outcome. Values on the y-axis reflect estimated differences in connectivity during successful gain outcomes versus unsuccessful gain outcomes extracted from whole brain contrast maps. Values come from single symptom models that adjust for sex, site, medication status, and connectivity calculated during the corresponding loss contrast. Symptom scores are presented as z-scores and reflect variation around average symptom severity in the sample.