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. 2022 Dec 31;64(2):100325. doi: 10.1016/j.jlr.2022.100325

Fig. 6.

Fig. 6

Endogenous lysoplasmalogen levels are sensitive to TMEM86a expression. A, B: Lipidomic analysis of the indicated lipid species following (A, C) overexpression, or (B) shRNA-mediated silencing of TMEM86a in BMDM (N = 5/group). Where indicated cells were also stimulated with 1 μM GW3965 for 16 h. C: Cells were cultured with 50 μg/ml AcLDL for 16 h as indicated after which membrane fluidity was measured (N = 6). The mean ± SEM are plotted. ∗ P<0.05, ∗∗ P <0.01, ∗∗∗ P <0.001, ∗∗∗∗ P < 0.0001.