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. 2023 Feb 14;14:824. doi: 10.1038/s41467-023-36561-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A retrospective series of 135 RT+qPCR+ nasopharyngeal swabs from COVID-19 patients, harboring Delta (n = 53) or Omicron BA.1 (n = 82) variants was collected. a Viral RNA loads, measured by RT-qPCR. The samples were ranked from high to low viral RNA load (low to high Ct). Viral titers were measured in Vero-TMPRSS2 (b) and IGROV-1 cells (c). Delta and Omicron BA.1-positive samples are depicted in the left and right panels, respectively. d Comparison of infectious titers for Delta and BA.1 samples in IGROV-1 cells (left panel). e Percentage of samples harboring detectable infectious Delta (middle panel) or BA.1 virus (right panel) using Vero and IGROV-1 cells. A two-sided Chi-square test was performed ****p < 0.0001. Source data are provided as a Source Data file.