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. 2023 Jan 20;9(2):270–282. doi: 10.1021/acsinfecdis.2c00418

Table 1. LasB Inhibitory Activities and Solubility of Substituted Benzothiazoles.

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a

Inhibition of purified LasB enzyme in Abz assay.

b

Inhibition at 25 μM inhibitor of elastin hydrolysis by dialyzed PAO1 culture supernatant in ECR assay.

c

Thermodynamic solubility in PBS (pH 7.4), measuring concentration of a saturated solution of compound at equilibrium.

d

not determined.