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. 2023 Jan 20;6(2):306–319. doi: 10.1021/acsptsci.2c00223

Figure 1.

Figure 1

Four-month-old Cx32def mice show smaller reductions in MNCV and CMAP after one month of daily cemdomespib therapy. (A) *, p < 0.0003 versus WT; #, p < 0.03 versus vehicle; ★, p < 0.004 versus vehicle; ^, p < 0.02 versus WT. Data are mean ± SD and were analyzed using an ordinary one-way ANOVA and Tukey’s test. Symbols indicate the response of individual animals in each group. (B) One month of 3 mg/kg drug therapy increased Hsp70 expression (arrow) in the sciatic nerve. Bottom blot shows Ponceau S staining as the loading control.