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Cemdomespib (Cmdespib) improved axonal myelination. (A) Representative 100× images of femoral nerve axons from 9-month-old WT, untreated Cx32def, and Cx32def mice treated for 5 months with 3 mg/kg cemdomespib. Femoral nerve g-ratios from 100 axons per mouse (n = 4) were plotted against the axon diameter from vehicle- or cemdomespib-treated Cx32def mice (B) and WT, vehicle or cemdomespib treated Cx32def mice (C). Scale bar, 20 μm.
