Table 2.
HTE population N = 2277 |
Non-HTE population N = 21,906 |
|
---|---|---|
Discontinuations, n (%) | 1032 (45) | 9049 (41) |
Months to discontinuation, median (IQR) | 27 (17, 46) | 23 (14, 34) |
Type of discontinuation, n (%) | ||
Core agent class switch (single baseline class) | 81 (8) | 3,241 (36) |
Same core agent class (single baseline class) | 50 (5) | 2055 (23) |
Multiple core agent classes switched | 603 (58) | 0 (0) |
Treatment gap > 45 days | 214 (21) | 3023 (33) |
No following regimen | 84 (8) | 730 (8) |
HTE heavily treatment-experienced; IQR interquartile range; n, number