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. 2023 Feb 12;23:63. doi: 10.1186/s12905-022-02140-y

Table 5.

Association between DASH-style diet and biochemical markers of participants

Variables DASH score Vegetables Fruits Nuts and Legumes Low fat dairy
β 95% CI P value β 95% CI P value β 95% CI P value β 95% CI P value β 95% CI P value
FBS
Crude  − 7.92  − 29.67 to 13.82 0.47  − 10.68  − 31.13 to 9.95 0.30  − 6.67  − 27.67 to 14.31 0.53  − 12.73  − 37.89 to 12.42 0.31  − 5.31  − 26.03 to 15.39 0.61
Model 1  − 3.82  − 25.08 to 17.43 0.72  − 11.53  − 31.32 to 8.24 0.25  − 7.28  − 27.51 to 12.93 0.47  − 14.84  − 38.96 to 9.28 0.22  − 8.22  − 28.25 to 11.80 0.41
Model 2 0.54  − 19.82 to 20.92 0.95  − 9.52  − 28.49 to 9.43 0.32  − 5.98  − 25.78 to 13.82 0.55  − 17.21  − 40.84 to 6.43 0.15  − 1.83  − 22.84 to 19.17 0.86
TG
Crude 8.07  − 19.79 to 35.94 0.56  − 1.78  − 28.69 to 25.12 0.89 8.71  − 18.53 to 35.95 0.52 8.82  − 23.33 to 40.98 0.58  − 17.13  − 43.83 to 9.57 0.20
Model 1 7.82  − 20.28 to 35.94 0.58  − 1.81  − 28.61 to 24.99 0.89 9.47  − 17.74 to 36.69 0.49 11.28  − 20.97 to 43.53 0.48  − 15.54  − 42.40 to 11.32 0.25
Model 2 9.18  − 20.54 to 38.91 0.54  − 1.16  − 29.01 to 26.66 0.93 11.06  − 17.04 to 39.16 0.43 8.19  − 25.32 to 41.72 0.62  − 15.11  − 44.80 to 14.58 0.31
HDL
Crude  − 1.06  − 4.86 to 2.74 0.58 0.09  − 3.69 to 3.89 0.96  − 0.50  − 4.35 to 3.34 0.79 2.32  − 2.18 to 6.84 0.30  − 1.34  − 5.12 to 2.44 0.48
Model 1  − 1.05  − 4.94 to 2.84 0.59 0.05  − 3.79 to 3.90 0.97  − 0.62  − 4.54 to 3.28 0.75 2.08  − 2.50 to 6.68 0.36  − 1.48  − 5.36 to 2.38 0.44
Model 2  − 0.49  − 4.18 to 3.19 0.79 0.20  − 3.48 to 3.89 0.91  − 0.53  − 4.27 to 3.19 0.77 2.72  − 1.56 to 7.01 0.21  − 0.34  − 4.29 to 3.61 0.86
LDL
Crude  − 5.07  − 18.47 to 8.32 0.45  − 7.22  − 20.16 to 5.71 0.27  − 6.009  − 19.16 to 7.14 0.36 4.31  − 11.29 to 19.93 0.58  − 7.77  − 20.70 to − 5.15 0.23
Model 1  − 5.14  − 18.86 to 8.57 0.45  − 7.39  − 20.51 to 5.72 0.26  − 5.50  − 18.89 to 7.88 0.41 4.42  − 11.45 to 20.30 0.58  − 7.61  − 20.84 to − 5.61 0.25
Model 2  − 5.41  − 18.69 to 7.87 0.42 0.28  − 19.83 to 5.81 0.28  − 4.54  − 17.65 to 8.56 0.49 6.47  − 8.88 to 21.83 0.40  − 16.28  − 29.7 to − 2.77 0.01
Total cholesterol
Crude  − 4.37  − 20.48 to 11.72 0.59  − 6.65  − 22.23 to 8.90 0.39  − 10.31  − 26.03 to 5.39 0.19 6.04  − 12.53 to 24.63 0.52  − 3.82  − 19.42 to 11.77 0.62
Model 1  − 4.12  − 20.60 to 12.36 0.62  − 6.42  − 22.29 to 9.36 0.42  − 10.27  − 26.30 to 5.76 0.20 6.64  − 12.29 to 25.58 0.48  − 4.04  − 20.04 to 11.59 0.61
Model 2  − 6.58  − 22.49 to 9.32 0.41  − 7.74  − 23.07 to 7.57 0.31  − 10.13  − 25.85 to 5.59 0.20 7.78  − 10.69 to 26.17 0.40  − 11.54  − 28.17 to 5.07 0.17
HbA1C
Crude  − 0.41  − 1.002 − .18 0.17  − 0.54  − 1.11 to 0.02 0.06  − 0.18  − 0.77 to 0.39 0.52  − 0.20  − 0.90 to 0.50 0.57  − 0.20  − 0.77 to 0.37 0.49
Model 1  − 0.30  − 0.89 to 0.27 0.29  − 0.56  − 1.11 to − 0.02 0.04  − 0.19  − 0.75 to 0.36 0.49  − 0.25  − 0.92 to 0.41 0.44  − 0.29  − 0.84 to 0.26 0.30
Model 2  − 0.31  − 0.90 to 0.27 0.28  − 0.55  − 1.09 to − 0.004 0.04  − 0.18  − 0.75 to 0.37 0.51  − 0.20  − 0.88 to 0.48 0.55  − 0.32  − 0.92 to 0.27 0.28
Creatinine
Crude  − 0.08  − 0.14 to 0.01 0.02  − 0.02  − 0.08 to 0.04 0.51  − 0.06  − 0.12 to 0.004 0.06  − 0.03  − 0.11 to 0.04 0.43  − 0.01  − 0.08 to 0.05 0.63
Model 1  − 0.07  − 0.14 to − 0.007 0.03  − 0.02  − 0.09 to 0.04 0.50  − 0.06  − 0.13 to 0.005 0.06  − 0.03  − 0.11 to 0.04 0.40  − 0.01  − 0.08 to 0.05 0.59
Model 2  − 0.08  − 0.15 to − 0.01 0.01  − 0.02  − 0.09 to 0.04 0.45  − 0.06  − 0.13 to − 0.001 0.04  − 0.03  − 0.12 to 0.04 0.37  − 0.04  − 0.11 to 0.02 0.17
BUN
Crude 0.08  − 1.88 to 2.05 0.93  − 0.95  − 2.80 to 0.90 0.31  − 0.52  − 2.41 to 1.35 0.57  − 0.91  − 3.16 to 1.34 0.42 1.28  − 0.55 to 3.13 0.17
Model 1 0.20  − 1.81 to 2.22 0.83  − 0.97  − 2.85 to 0.91 0.30  − 0.56  − 2.49 to 1.36 0.56  − 0.93  − 3.23 to 1.37 0.42 1.29  − 0.60 to 3.19 0.17
Model 2  − 0.11  − 2.08 to 1.85 0.91  − 1.06  − 2.89 to 0.75 0.24  − 0.69  − 2.55 to 1.16 0.45  − 0.66  − 2.88 to 1.55 0.55 0.60  − 1.36 to 2.57 0.54
ACR
Crude  − 22.07  − 69.57 to 25.43 0.35  − 45.05  − 90.95 to 0.84 0.05  − 39.54  − 86.32 to 7.23 0.09  − 76.73  − 130.05 to − 23.42 0.005 20.57  − 25.99 to 67.13 0.38
Model 1  − 20.15  − 68.21 to 27.89 0.40  − 44.99  − 90.82 to 0.84 0.05  − 37.41  − 84.37 to 9.54 0.11  − 78.54  − 131.84 to − 25.24 0.004 14.27  − 32.76 to 61.31 0.54
Model 2  − 29.28  − 77.9 to 19.33 0.23  − 43.44  − 89.02 to 2.13 0.06  − 37.66  − 84.55 to 9.23 0.11  − 83.61  − 136.91 to − 30.31 0.002 5.30  − 45.01 to 55.63 0.83
Hb
Crude 0.67 0.10 to 1.24 0.02 0.02  − 0.53 to 0.58 0.92 0.06  − 0.49 to 0.63 0.81 0.53  − 0.12 to 1.19 0.11 0.47  − 0.07 to 1.02 0.09
Model 1 0.65 0.07 to 1.23 0.02 0.03  − 0.53 to 0.59 0.90 0.09  − 0.47 to 0.66 0.74 0.53  − 0.13 to 1.20 0.11 0.46  − 0.09 to 1.02 0.10
Model 2 0.61 0.02 to 1.19 0.04 0.03  − 0.52 to 0.59 0.90 0.09  − 0.47 to 0.67 0.73 0.56  − 0.11 to 1.23 0.10 0.41  − 0.18 to 1.01 0.17
Postprandial BS
Crude  − 9.83  − 32.77 to 13.10 0.39  − 18.43  − 39.94 to 3.07 0.09  − 4.37  − 26.48 to 17.73 0.69  − 12.50  − 38.88 to 13.87 0.34  − 12.22  − 33.89 to 9.45 0.26
Model 1  − 6.52  − 29.15 to 16.11 0.56  − 19.03  − 39.95 to 1.89 0.07  − 4.43  − 26.06 to 17.19 0.68  − 13.46  − 39.18 to 12.25 0.30  − 14.93  − 36.18 to 6.31 0.16
Model 2  − 2.68  − 24.44 to 19.07 0.80  − 16.51  − 36.37 to 3.34 0.10  − 3.06  − 23.64 to 17.50 0.76  − 13.25  − 37.87 to 11.37 0.28  − 6.41  − 28.17 to 15.33 0.55
Alb
Crude  − 2.48  − 7.63 to 2.69 0.34  − 0.14  − 5.03 to 4.74 0.95  − 3.28  − 8.20 to 1.63 0.18  − 7.04  − 12.82 to − 1.27 0.01  − 0.01  − 4.90 to 4.87 0.99
Model 1  − 1.93  − 7.12 to 3.26 0.46  − 0.20  − 5.08 to 4.67 0.93  − 3.26  − 8.18 to 1.66 0.19  − 7.75  − 13.31 to − 1.82 0.01  − 0.67  − 5.59 to 4.24 0.78
Model 2  − 2.38  − 7.50 to 2.82 0.37 0.24  − 4.55 to 5.04 0.92  − 3.08  − 7.90 to 1.74 0.20  − 7.16  − 12.80 to − 1.52 0.01  − 349  − 8.59 to 1.61 0.17
SBP
Crude  − 4.97  − 12.38 to 2.44 0.18  − 9.09  − 15.94 to − 2.25 0.01  − .96  − 8.13 to 6.21 0.79 0.057  − 8.004 to 9.15 0.89  − 0.05  − 7.12 to 7.02 0.98
Model 1  − 4.59  − 11.94 to 2.57 0.21  − 9.22  − 15.95 to − 2.49 0.008  − 1.80  − 8.90 to 5.28 0.61  − 0.07  − 8.54 to 8.39 0.98 0.22  − 6.81 to 7.26 0.94
Model 2  − 5.72  − 13.231.78 0.13  − 9.87  − 16.62 to − 3.12 0.005  − 1.75  − 8.89 to 5.37 0.62  − 1.63  − 4.95 to 8.19 0.70  − 1.34  − 8.90 to 6.22 0.7
DBP
Crude  − 6.50  − 11.91 to − 1.08 0.01  − 4.17  − 9.47 to 1.12 0.12  − 0.74  − 6.18 to 4.68 0.78 3.06  − 3.39 to 9.51 0.34  − 6.41  − 11.63 to − 1.20 0.01
Model 1  − 6.72  − 12.17 to − 1.26 0.01  − 4.14  − 9.44 to 1.14 0.12  − 1.008  − 6.42 to 4.44 0.71 2.92  − 3.50 to 9.39 0.37  − 6.25  − 11.51 to − 0.99 0.02
Model 2  − 7.40  − 12.97 to − 1.83 0.01  − 4.74  − 10.12 to 0.64 0.08  − 1.005  − 6.56 to 4.55 0.72 1.61  − 4.95 to 8.19 0.62  − 7.53  − 13.21 to − 1.86 0.01
Variables Whole grain Sodium Red meat Sweetened beverages
β 95% CI P value β 95% CI P value β 95% CI P value β 95% CI P value
FBS
Crude 4.81  − 16.04 to 25.67 0.64 18.21  − 6.60 to 43.03 0.14 13.79  − 34.13 to 6.54 0.18 2.89  − 22.72 to 16.93 0.77
Model 1  − 0.92  − 21.23 to 19.38 0.92 14.73  − 9.35 to 38.82 0.22 5.82  − 26.79 to 15.14 0.58 3.85  − 15.54 to 23.25 0.69
Model 2 3.26  − 16.94 to 23.47 0.74 16.79  − 8.83 to 42.43 0.19 1.02  − 22.82 to 20.77 0.92 3.41  − 15.80 to 22.63 0.72
TG
Crude  − 15.94  − 42.86 to 10.97 0.24 2.85  − 35.37 to 29.67 0.86  − 2.33  − 29.08 to 24.41 0.86 7.82  − 17.88 to 33.52 0.54
Model 1  − 14.44  − 41.66 to 12.70 0.29 1.18  − 31.47 to 33.83 0.94 3.15  − 24.96 to 31.28 0.82 5.72  − 20.38 to 31.82 0.66
Model 2  − 13.17  − 41.77 to 15.42 0.36 1.20  − 33.58 to 35.99 0.94 5.11  − 25.99 to 36.22 0.74 4.93  − 22.37 to 32.24 0.72
HDL
Crude 0.95  − 2.85 to 4.77 0.62  − 2.22  − 6.78 to 2.34 0.33  − 1.05  − 5.15 to 2.14 0.41 0.76  − 2.86 to 4.39 0.67
Model 1 0.73  − 3.18 to 4.65 0.71  − 2.63  − 7.29 to 2.02 0.26  − 2.08  − 5.99 to 1.82 0.29 1.11  − 2.63 to 4.86 0.55
Model 2 1.30  − 2.49 to 5.09 0.49  − 3.42  − 7.98 to 1.12 0.13  − 0.22  − 4.20 to 3.75 0.91 0.88  − 2.73 to 4.50 0.62
LDL
Crude  − 4.24  − 17.32 to 8.83 0.52 9.76  − 25.38 to 5.58 0.21 2.26  − 10.55 to 15.08 0.72 2.06  − 14.51 to 10.38 0.74
Model 1  − 3.56  − 17.00 to 9.87 0.60 9.62  − 25.59 to 6.33 0.23 3.56  − 10.16 to 17.30 0.60 2.86  − 15.71 to 9.99 0.66
Model 2  − 5.64  − 18.98 to 7.69 0.40 13.76  − 29.96 to 2.44 0.09 0.57  − 13.65 to 14.80 0.93  − 0.48  − 13.21 to 12.25 0.94
Total cholesterol
Crude  − 3.70  − 19.40 to 12.00 0.64 10.25  − 29.02 to 8.51 0.28 10.09  − 5.30 to 25.48 0.19 2.90  − 17.83 to 12.02 0.70
Model 1  − 3.93  − 20.11 to 12.24 0.63 9.60  − 28.85 to 9.65 0.32 12.82  − 3.61 to 29.27 0.12 3.14  − 18.61 to 12.32 0.68
Model 2  − 8.44  − 24.51 to 7.62 0.29 6.57  − 26.22 to 13.57 0.50 6.36  − 10.95 to 23.67 0.46 2.28  − 17.65 to 13.08 0.76
HbA1C
Crude 0.36  − 0.21 to 0.93 0.21 0.11  − 0.58 to 0.81 0.73  − 0.45  − 1.01 to 0.10 0.10  − 0.14  − 0.69 to 0.41 0.61
Model 1 0.20  − 0.35 to 0.76 0.47 0.01  − 0.66 to 0.68 0.96  − 0.24  − 0.82 to 0.33 0.40 0.04  − 0.49 to 0.58 0.86
Model 2 0.20  − 0.37 to 0.78 0.49 0.05  − 0.66 to 0.76 0.88  − 0.22  − 0.84 to 0.40 0.48  − 0.01  − 0.57 to 0.53 0.94
Creatinine
Crude  − 0.056  − 0.12 − 0.01 0.09  − 0.01  − 0.09 to 0.06 0.64 0.05  − 0.11 to 0.01 0.12  − 0.02  − 0.09 to 0.03 0.36
Model 1  − 0.06  − 0.13 − 0.006 0.07  − 0.02  − 0.10 to 0.05 0.55 0.05  − 0.12 to 0.02 0.16  − 0.02  − 0.09 to 0.04 0.45
Model 2  − 0.07  − 0.14 − 0.01 0.02  − 0.01  − 0.09 to 0.07 0.81 0.096  − 0.16 to 0.02 0.009  − 0.02  − 0.08 to 0.04 0.51
BUN
Crude 0.73  − 1.13 to 2.60 0.43  − 1.79  − 4.02 to 0.42 0.11 0.99  − 0.85 to 2.84 0.29 0.14  − 1.63 to 1.92 0.87
Model 1 0.66  − 1.27 to 2.58 0.49  − 1.85  − 4.13 to 0.42 0.10 1.41  − 0.56 to 3.38 0.16 0.26  − 1.58 to 2.11 0.77
Model 2 0.16  − 1.74 to 2.06 0.86  − 1.51  − 3.80 to 0.76 0.19 0.63  − 1.41 to 2.68 0.53 0.26  − 1.53 to 2.07 0.76
ACR
Crude 51.91 5.95 to 97.86 0.30 15.66  − 72.07 to 40.57 0.58  − 16.41  − 62.41 to 29.59 0.48 21.57  − 22.94 to 66.08 0.33
Model 1 46.38  − 0.34 to 93.11 0.20  − 19.58  − 76.36 to 37.18 0.49  − 12.14  − 60.83 to 36.54 0.62 29.97  − 15.17 to 75.11 0.19
Model 2 38.55  − 9.22 to 86.32 0.11  − 6.08  − 64.52 to 52.53 0.83  − 38.04  − 89.28 to 13.19 0.14 29.93  − 15.72 to 75.58 0.19
Hb
Crude 0.44  − 0.11 to 1.002 0.11  − 0.05  − 0.73 to 0.62 0.87 0.96 0.44 to 1.49 0.40  − 0.18  − 0.17 to 0.35 0.49
Model 1 0.48  − 0.08 to 1.54 0.09  − 0.07  − 0.75 to 0.61 0.83 0.97 0.41 to 1.53 0.58  − 0.21  − 0.76 to 0.33 0.44
Model 2 0.40  − 0.17 to 0.98 0.16 0.002  − 0.70 to 0.71 0.99 0.91 0.31 to 1.52 0.60  − 0.20  − 0.76 to 0.34 0.46
Postprandial BS
Crude 14.85  − 6.90 to 36.62 0.17 17.66  − 8.47 to 43.79 0.18 19.07  − 40.48 to 2.34 0.08 3.03  − 23.85 to 17.85 0.77
Model 1 10.35  − 11.24 to 31.94 0.34 15.86  − 9.85 to 41.58 0.22 11.46  − 33.82 to 10.88 0.31 2.41  − 18.31 to 23.14 0.81
Model 2 16.23  − 4.46 to 36.93 0.12 16.21  − 10.63 to 43.06 0.23 1.50  − 24.25 to 21.24 0.89 0.34  − 20.28 to 19.60 0.97
Alb
Crude  − 6.85 2.11 to 11.59 0.005  − 1.66  − 7.57 to 4.23 0.57  − 0.32  − 5.21 to 4.57 0.89  − 2.18  − 6.84 to 2.47 0.35
Model 1  − 6.22 1.40 to 11.04 0.01  − 2.49  − 8.42 to 3.42 0.40  − 0.39  − 4.74 to 5.54 0.87  − 1.29  − 6.4 to 3.45 0.59
Model 2  − 5.66 0.84 to 10.48 0.02  − 2.56  − 8.56 to 3.43 0.39  − 1.73  − 7.10 to 3.63 0.52  − 0.70  − 5.41 to 4.01 0.76
SBP
Crude 3.74  − 3.34 to 10.82 0.29 3.01  − 11.54 to 5.51 0.48 2.13  − 4.93 to 9.19 0.55 0.88  − 5.88 to 7.64 0.79
Model 1 3.62  − 3.45 to 10.70 0.31 3.93  − 12.40 to 4.53 0.35 1.29  − 6.05 to 8.65 0.72 1.27  − 5.52 to 8.07 0.71
Model 2 3.02  − 4.23 to 10.27 0.41 3.39  − 12.18 to 5.39 0.44 1.34  − 9.24 to 6.55 0.73 1.55  − 5.36 to 8.47 0.65
DBP
Crude  − 6.47  − 11.72 to − 1.22 0.01 6.58  − 13.19 to − 0.51 0.03 0.78  − 6.07 to 4.50 0.76 2.62  − 7.72 to 2.48 0.31
Model 1  − 6.21  − 11.53 to − 0.88 0.02 7.10  − 13.48 to − 0.72 0.02 2.23  − 7.80 to 3.34 0.42 3.20  − 8.39 to 1.98 0.22
Model 2  − 6.92  − 12.40 to − 1.44 0.01 6.81  − 13.52 to − 0.10 0.04 4.07  − 10.10 to 1.95 0.18 3.42  − 8.76 to 1.92 0.20

Obtained from General Linear Model (GLM). Significant items with a P value ≤ 0.05 are bolded

Model 1: Adjusted for energy intake, age, physical activity, body mass index

Model 2: model 1 + diabetes duration, cardiovascular diseases history, and drug usage (angiotensin receptor blockers; angiotensin converting enzyme inhibitors, beta-blockers, metformin, sulphonyl urea, and insulin)

CI Confidence interval, Cr Creatinine, DASH Dietary approaches to stop hypertension diet, DBP Diastolic blood pressure, SBP Systolic blood pressure, FBS Fasting blood sugar, HbA1c Glycosylated hemoglobin, HDL High-density lipoprotein, LDL Low-density lipoprotein, TC Total cholesterol, TG Triglycerides, Alb Albumin, BS Blood sugar, ACR Albumin creatinine ratio, BUN Blood urea nitrogen