Fig. 4.
Association of pre-pregnancy BMI (ppBMI) with plasma lipidomic profiles at preconception, pregnancy and postpartum using trio subjects (n = 252). A Histogram of ppBMI. B Forest plots (error bar: 95% CI) of the ppBMI association studies at three time points. Diamond—Padj ≥ 0.05 (grey), circle—Padj < 0.05 and square—Padj < 1.00E−5. C Venn diagram of significant lipid species in three studies. D Scatter plots of effect sizes (% change in lipid concentration per unit BMI). E Thirty-eight unique pregnancy-related lipid signatures. F Forty-nine common lipid signatures in three studies