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. 2023 Feb 14;11:27. doi: 10.1186/s40168-023-01470-9

Table 3.

HBIS positively correlated to EFC_1 and manually identified with MetaCyc database

Spearman correlation (adj. P-value < 0.05)
EC name EC number EFC_4 EFC_1 Related product effects Ref
Isochorismate synthase 5.4.4.2  − 0.541970 0.311153 Production of the precursor of vitamin K2 [39]
1,4-dihydroxy-2-naphthoyl-CoA synthase 4.1.3.36  − 0.543416 0.316668 Production of the precursor of vitamin K2 [40]
Quinolinate synthase 2.5.1.72 - 0.266977 Precursor of niacin and indirectly of vitamin B3 [41]
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase 1.17.7.3  − 0.598568 0.333534 Production of phosphoantigen [37]