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. 2023 Feb 14;22:54. doi: 10.1186/s12936-023-04483-9

Table 2.

Characteristics for patient profiles analysed in stage 1 of the WWARN PCEa

Characteristics All patients
(n = 714 patients)
Successful analysis
(n = 678 patients)
Unsuccessful analysis
(n = 36 patients)
Number of parasite measurements
 Median, IQR 5, 5–6 6, 5–7 3, 3–3
 Range 3–14 3–14 3–5
 < 3 0 0 0
 3 37 (5.2%) 2 (0.3%) 35 (97.2%)
 4 107 (15%) 107 (15.8%) 0
 5 217 (30.4%) 216 (31.9%) 1 (2.8%)
 6 182 (25.5%) 182 (26.8%) 0
 7 110 (15.4%) 110 (16.2%) 0
 ≥ 8 61 (8.5%) 61 (9%) 0
Sex
 Female 135 (18.9%) 128 (18.9%) 7 (19.4%)
 Male 579 (81.1%) 550 (81.1%) 29 (80.6%)
Age (years)
 Median, IQR 35, 24–49 34, 23–48 37, 23–44.5
 Range 3–96 3–96 14–68
Weight (kg)
 Median, IQR 58, 50–67 58, 50.4–67 59, 51.5–68
 Range 11–118 11–118 35–80.5
Previous malaria
 No 511 (71.6%) 489 (72.1%) 22 (61.1%)
 Yes 203 (28.4%) 189 (27.9%) 14 (38.9%)
Days of preceding fever
 Median, IQR 4, 3–7 4, 3–7 4, 3–7
 Range 0–44b 0–44c 2–14d
Initial parasitaemia (/μL of blood)
 Median, IQR 1898, 463–6276 2056, 533–6398 127, 56–555
 Range 28–325,294 28–325,294 28–16,748
Treatment
Uncomplicated malaria
 Artemether–lumefantrine 320 (44.8%) 301 (44.3%) 19 (52.8%)
 Artesunate–mefloquine 115 (16.1%) 111 (16.4%) 4 (11%)
 Chloroquine 176 (24.7%) 174 (25.7%) 2 (5.6%)
Severe malaria
 Artemether–lumefantrine followed by artesunate (intravenous) 16 (2.2%) 15 (2.2%) 1 (2.8%)
 Artesunate (intravenous) followed by artemether–lumefantrine 87 (12.2%) 77 (11.4%) 10 (27.8%)

aWorldwide Antimalarial Resistance Network’s Parasite Clearance Estimator

IQR: inter-quartile range; kg: kilograms; μL: microlitre

b18 patients did not have data for days of preceding fever

c2 patients did not have data for days of preceding fever

d16 patients did not have data for days of preceding fever