Table 3.
Treatment | WWARN PCEa | Bayesian hierarchical modelling |
---|---|---|
Uncomplicated malaria | ||
Artemether–lumefantrine (n) | 301 | 320 |
Mean (hours) | 2.845 | 1.940 |
Median (hours) | 2.634 | 1.940 |
95% CI & CrI (hours) | [1.568, 5.254] | [1.808, 2.116] |
Artesunate–mefloquine (n) | 111 | 115 |
Mean (hours) | 3.029 | 1.929 |
Median (hours) | 2.529 | 1.932 |
95% CI & CrI (hours) | [1.466, 7.683] | [1.741, 2.137] |
Chloroquine (n) | 174 | 176 |
Mean (hours) | 3.599 | 2.861 |
Median (hours) | 3.265 | 2.865 |
95% CI & CrI (hours) | [1.867, 7.324] | [2.689, 3.044] |
Severe malaria | ||
Artemether–lumefantrine followed by artesunate (intravenous) (n) | 15 | 16 |
Mean (hours) | 2.485 | 1.970 |
Median (hours) | 2.118 | 1.961 |
95% CI & CrI (hours) | [1.513, 4.867] | [1.622, 2.429] |
Artesunate (intravenous) followed by artemether–lumefantrine (n) | 77 | 87 |
Mean (hours) | 2.532 | 1.792 |
Median (hours) | 2.275 | 1.793 |
95% CI & CrI (hours) | [1.252, 4.181] | [1.584, 2.009] |
aWorldwide Antimalarial Resistance Network Parasite Clearance Estimator
CI: Confidence interval; CrI: Credible interval