Skip to main content
. 2023 Feb 14;8:18. doi: 10.1038/s41541-023-00610-4

Fig. 8. CMS:O/W adjuvant induces distinct gene expression profiles from AddaVax, including enhanced type I IFN-dependent ISG expression in the draining lymph node.

Fig. 8

a, b Young (3-month-old) BALB/c mice were injected with PBS, AddaVax and CMS:O/W adjuvant. 24 h later muscle tissue at the injection sites (a) and dLNs (b) were collected to assess gene expression profiles by qPCR. Results are reported as relative expression compared to Rp13a. N = 4 mice per group. * and ** respectively indicate p < 0.05 and 0.01. Statistical significance was determined by one-way ANOVA corrected for multiple comparisons after Log-transformation of the raw data. Box-and-whisker plots represent the minimum, first quartile, median, third quartile, and maximum value. Each symbol represents an individual sample. The color code indicates comparisons among experimental groups. Source data are provided as Supplementary Data.