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Evolution of colistin resistance in colistin-susceptible and colistin-resistant E. coli. The fold change of colistin MIC was detected after colistin-susceptible E. coli ATCC 25922 (A) and colistin-resistant E. coli SHP45 (B) were treated with 0.5× MIC colistin alone or in combination with IBG at 5 μg/mL or 10 μg/mL in vitro.
