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Comparison between cfDNA and wcDNA mNGS for clinical utility in CNS infections. (A) Comparison of detection rates and coincidence rates. (B) Contingency tables for clinical diagnosis with cfDNA mNGS and wcDNA mNGS sets, respectively. (C) Advantages of cfDNA mNGS over wcDNA mNGS. (D) Ratio of RPM for pathogens of the same patients detected by both strategies.
