TABLE 2.
Patient characteristicsa
| Parameter | Value for group |
P value | ||
|---|---|---|---|---|
| All patients (n = 155) | Patients without ESBL-PE (n = 124) | Patients with ESBL-PE (n = 31) | ||
| Demographic characteristics | ||||
| Median patient age (yrs) (25th–75th percentiles) | 64 (54–74) | 65 (54–74) | 61 (55–76) | 0.90 |
| No. of patients of sex (M/F) | 105/50 | 82/42 | 23/8 | 0.39 |
| Median simplified acute physiology score II (25th–75th percentiles) | 32 (21–45) | 31 (19–46) | 36 (25–44) | 0.22 |
| No. (%) of patients with type of ICU admission | ||||
| Medical | 79 (50) | 63 (50) | 16 (52) | 0.81 |
| Surgical, urgent | 35 (22) | 27 (22) | 8 (26) | |
| Surgical, scheduled | 41 (26) | 34 (28) | 7 (22) | |
| No. (%) of patients with cause(s) of ICU admission | ||||
| Sepsis, septic shock | 49 (31) | 39 (31) | 10 (32) | 0.06 |
| Acute respiratory failure | 13 (8) | 7 (9) | 4 (12) | |
| Postoperative care | 49 (32) | 40 (32) | 9 (29) | |
| Hemorrhagic shock | 33 (21) | 26 (21) | 7 (23) | |
| Coma, epilepsy, neurological failure | 6 (4) | 36 (5) | 0 (0) | |
| Cardiogenic shock/cardiorespiratory arrest | 5 (3) | 4 (3) | 1 (3) | |
| No. (%) of patients with ESBL-PE colonization risk factor | ||||
| Hospitalization for ≥48 h in the previous 12 mo | 91 (58) | 65 (52) | 26 (84) | 0.01 |
| Antibiotic therapy in the previous 3 mo | 58 (37) | 43 (35) | 15 (48) | 0.16 |
| Hospital stay of ≥5 days before ICU admission | 55 (35) | 40 (32) | 15 (48) | 0.09 |
| Immunosuppression | 27 (17) | 23 (18) | 4 (13) | 0.46 |
| Colonization with ESBL-PE in the previous 6 mo | 21 (13) | 10 (8) | 11 (35) | <0.001 |
| Life in an institution or nursing home | 8 (5) | 6 (5) | 2 (6) | 0.72 |
| Travel in a zone where ESBL-PE are endemic in the previous 12 mo | 8 (5) | 6 (5) | 2 (6) | 0.72 |
| Chronic renal replacement | 4 (3) | 0 (0) | 4 (13) | <0.001 |
| Recurrent urinary tract infections | 1 (1) | 1 (1) | 0 (0) | 0.61 |
| Total no. of risk factors per patient (25th–75th percentiles) | 2 (0–3) | 1 (0–2) | 3 (1–3.5) | 0.01 |
| Median length of stay (days) (25th–75th percentiles) in: | ||||
| ICU | 3 (2–5.5) | 3 (2–5) | 3 (2–6) | 0.80 |
| Hospital | 12 (7–22) | 12 (7–20) | 11 (4–18) | 0.37 |
M, male; F, female.