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. 2022 Dec 20;11(1):e02385-22. doi: 10.1128/spectrum.02385-22

TABLE 3.

Characteristics of patients with treatment failurea

Age Clinical indication Pathogen Dosing Comment
30 BSI with abscess MRSA 1,500 mg ×1b Recurrence of purulent cellulitis with abscess due to intramuscular heroin injections into wound
34 OM, ABSSTI MSSA 1,500 mg weekly ×2c Assault victim that self-discharged 3 times without indicated surgical source control
52 ABSSTI, BSI, OM MRSA 1,500 mg ×1b Multiple self-discharges during which the patient declined the removal of the retained needle and incision and drainage
55 ABSSTI with BSI MRSA 1,500 mg ×1b Burn victim with acute on chronic worsening of wounds, unclear if recurrence or new infection
50 BSI CoNSd 1,500 mg ×1b Readmitted with concern for septic arthritis of the ankle
a

BSI, bloodstream indications; MRSA, methicillin-resistant Staphylococcus aureus; OM, osteomyelitis; ABSSTI, acute bacterial skin and soft tissue infections; MSSA, methicillin-sensitive Staphylococcus aureus, AMA, against medical advice; CoNS, coagulase negative Staphylococcus aureus.

b

Received initial treatment course with IV vancomycin prior to dalbavancin.

c

Received cefazolin prior to dalbavancin.

d

4 species of CoNS.