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Cytotoxicity assays of tigecycline, eravacycline, omadacycline, and sarecycline in the differentiated THP-1 cell lines. All data are shown as the mean values ± standard deviations (n = 4). At the concentration of 40 mg/L, the cell viability for OMC was significantly lower than TGC, ERC, and SAC (two-independent-sample t test, P < 0.05). *, P < 0.05; **, P < 0.01.
