FIG 7.

Success of the D39 sdhB^G14R genotype during invasive pneumonia in mice. Mice were infected intranasally with 1 × 10⁶ CFU of either passaged (A) or nonpassaged (B) stocks of D39N prepared from agar plate 1, as depicted in Fig. 5. Graphs show the bacterial density in the blood at 24 h postinfection (gray bars on the left y axis) and the frequency of the sdhB^G14R genotype in the total recovered pneumococci at 24 h postinfection (blue lines on the right y axis). The total recovered pneumococci are those isolated from the lungs of mice that were nonbacteremic at the time of death or those pooled from the lungs and blood of mice that were bacteremic at the time of death.