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Viability of retinal cells in hypoxia with ONBs. Muller and R28 retina cell viability after 6 hours in hypoxia (5% O2) with varying concentrations of NBs or no treatment. Shell (no O2) groups were treated with a concentration of 0.5 mg/mL. Data are shown as mean ± standard deviation. NT, no treatment. † Significant difference to NT Normoxia. ‡ Significant difference to NT hypoxia (n = 8). ****P < 0.00001; ***P < 0.0001; **P < 0.001.
