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Maximal mitochondria respiration after hypoxia and ONB treatment. After exposing R28 and Muller cells to 6 hours of hypoxia with three concentrations of oxygen-loaded dextran NBs, a dose-dependent protection of mitochondria maximal respiration was observed. Cells were seeded at 5000 cells/well and treated with an FCCP concentration of 1.5 µM. NT, no treatment. Data are shown as the mean ± standard deviation, with n = 8. ****P < 0.00001; ***P < 0.0001.
