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. 2023 Jan 9;13(2):e2849. doi: 10.1002/brb3.2849

TABLE 2.

Symptoms of chronic fatigue during all time intervals assessed retrospectively

Prior to COVID‐19 0–4 weeks 4–12 weeks >12 weeks p‐value vs. baseline (men; women)*
Men Women p‐value Men Women p‐value Men Women p‐value Men Women p‐value 0–4 weeks 4–12 weeks >12 weeks
1.1 Persistent fatigue, not caused by an effort, persisting after rest 13 (20.97) 59 (24.58) 0.551 48 (77.42) 214 (88.80) 0.020 41 (66.13) 191 (79.25) 0.030 29 (50.00) 148 (62.45) 0.083 <0.001; <0.001 <0.001; <0.001 <0.001; <0.001
1.2 Sore throat 2 (3.23) 12 (4.98) 0.742 14 (22.58) 88 (36.51) 0.039 5 (8.06) 47 (19.50) 0.037 3 (5.17) 21 (8.86) 0.434 0.001; <0.001 0.180; <0.001 0.563; 0.051
1.3 Self‐reported lymph node enlargement 1 (1.61) 8 (3.32) 0.691 5 (8.06) 43 (17.84) 0.078 3 (4.84) 32 (13.28) 0.075 0 (0.00) 14 (5.91) 0.080 0.102; <0.001 0.157; <0.001 0.317; 0.134
1.4 Myalgia 6 (9.68) 31 (12.86) 0.495 31 (50.00) 150 (62.24) 0.080 20 (32.26) 104 (43.15) 0.120 12 (20.69) 72 (30.38) 0.143 <0.001; <0.001 <0.001; <0.001 0.034; <0.001
1.5 Arthralgia 0 (0.00) 18 (7.47) 0.029 4 (6.45) 41 (17.01) 0.044 4 (6.45) 33 (13.69) 0.120 2 (3.45) 26 (10.97) 0.085 0.045; <0.001 0.046; 0.002 0.157; 0.102
1.6 Headache 9 (14.52) 60 (24.90) 0.082 32 (51.61) 177 (73.44) <0.001 27 (43.55) 138 (57.26) 0.053 18 (31.03) 100 (42.19) 0.120 <0.001; <0.001 <0.001; <0.001 0.002; <0.001
1.7 Non‐restorative sleep 6 (9.68) 46 (19.09) 0.080 29 (46.77) 158 (65.56) 0.007 24 (38.71) 126 (52.28) 0.057 15 (25.86) 96 (40.51) 0.039 <0.001; <0.001 <0.001; <0.001 0.006; <0.001
1.8 Prolonged postexercise fatigue 6 (9.68) 42 (17.43) 0.137 43 (69.35) 195 (80.91) 0.048 39 (62.90) 160 (66.39) 0.607 23 (39.66) 119 (50.21) 0.149 <0.001; <0.001 <0.001; <0.001 <0.001; <0.001

Note: Data are presented as numbers (n) and percentages (%), *Cochran's Q test for dependent variable. The Bonferroni correction was used for pairwise comparisons, and the significance level was set below .008.