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. 2023 Feb 15;133(4):e160959. doi: 10.1172/JCI160959

Figure 11. Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes.

Figure 11

DNA methylation–dependent regulation of genes implicated in pathways that are clinically relevant to the progression of diabetic nephropathy. Erosion of DNA methylation is associated with the loss of protection and the activation of core pathways associated with DN risk in type 1 diabetes.