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. 2023 Jan 25;10:1065779. doi: 10.3389/fcvm.2023.1065779

TABLE 5.

Subgroup analysis on the association between frailty score and length of hospital stay.

Studies (n) Mean difference (95% CI) P-value Q-test I2 (%) P between Effect size (95% CI) P-value Q-test I2 (%) P between
Length of follow-up
≤30 days 6 1.861 (1.619, 2.104) <0.001 9.015 44.537 0.292 0.181 (−0.001, 0.363) 0.051 718.021 99.304*** 0.020
>30 days 3 4.559 (−0.450, 9.568) 0.074 65.562 96.949*** 0.471 (0.307, 0.634) <0.001 3.921 48.988
Mean age
<70 years old 3 1.949 (1.806, 2.092) <0.001 2.919 31.493 0.431 0.283 (0.052, 0.514) 0.016 684.084 99.708*** 0.630
70 years old and more 5 3.462 (−1.725, 8.649) 0.191 54.892 92.713*** 0.257 (−0.025, 0.540) 0.074 19.311 79.287**
Surgery type
Vascular surgeries 8 2.705 (0.048, 5.362) 0.046 446.545 98.432*** 0.506 0.327 (0.214, 0.439) <0.001 88.563 92.096*** 0.002
Amputation only 1 1.800 (1.557, 2.043) <0.001 <0.001 <0.001 0.144 (0.125, 0.164) <0.001 <0.001 <0.001
Severity
Mild 6 3.151 (1.774, 4.528) <0.001 444.579 98.875*** 0.009 0.327 (0.175, 0.480) <0.001 767.586 99.349*** 0.043
Severe 3 −0.816 (−3.479, 1.846) 0.548 0.405 <0.001 0.023 (−0.228, 0.275) 0.856 0.730 <0.001
Amputation and foot ulcer history
No 7 2.770 (−1.040, 6.580) 0.154 244.656 97.548*** 0.669 0.249 (0.024, 0.475) 0.030 75.507 92.054*** 0.873
Yes 2 1.938 (1.757, 2.119) <0.001 2.588 61.366 0.277 (0.017, 0.538) 0.037 683.803 99.854***
Wound
Open wound 3 1.775 (1.379, 2.172) <0.001 2.532 21.018 0.637 0.163 (0.106, 0.220) <0.001 3.216 37.815 0.003
Others 6 2.728 (−1.211, 6.667) 0.175 443.256 98.872*** 0.376 (0.249, 0.503) <0.001 60.746 91.769***

CI, confidence interval, no medication subgroups data due to all studies belong to no ploy-medication group. **p < 0.01, ***p < 0.001. The bold values mean significant p-values.