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. Author manuscript; available in PMC: 2023 Feb 14.
Published in final edited form as: Blood Rev. 2020 Jul 10;46:100732. doi: 10.1016/j.blre.2020.100732

Figure 3:

Figure 3:

(A) DNA readout from baseline hybridization-capture based NGS panel (myTYPE) demonstrating clonality of heavy chains. With respect to MRD assessment, this baseline assay not only provides a barcode for disease tracking but also supplies prognostic information from the target mutational panel revealing common drivers, translocation, and copy number changes. (B) RNA-seq readout of immunoglobulin gene expression in an MRD assessment of CD138-selected cells showing clonal IgH VJ and IgK VJ (D not included for graphical purposes). (C) RNA-seq readout from immunoglobulin gene expression in a normal sample showing no clonality.