FIGURE 1.

Droplets plot of the digital droplet polymerase chain reaction assay. ALK wild‐type positive and negative droplets are presented as green and grey dots, respectively. L1196M ALK mutation positive and negative droplets are presented as blue and grey dots, respectively. Thirty‐one samples were analysed. Sample number one is the large‐sized tumour cells purified as the CD30 positive population from the blood sample at onset; sample number two is the small‐sized tumour cells purified as the CD30 negative population from the blood cells at onset; sample numbers three to 19 are the blood samples from onset to the first relapse over time, days 1, 7, 13, 21, 28, 33, 41, 52, 73, 79, 91, 96, 112, 118, 126, 142, and 161 from treatment initiation, respectively; sample numbers 20–26 are blood samples from the first to the second relapse over time, days 189, 205, 215, 219, 221, 243, and 272 from treatment initiation, respectively; sample number 27 is the blood sample at the second relapse; sample number 28 is the pulmonary tumour sample; sample number 29 is the lymph node lesion of another patient with common type anaplastic large cell lymphoma; sample number 30 is a blood sample from a healthy donor; sample number 31 is a negative control (distilled water).