Table 4.

Hazard Ratios of All-cause and cause-specific mortality by number of vessels and Index of Diffusion (ID)

Model 1				Model 2
	All-Cause Mortality	CVD-specific Mortality	CHD-specific Mortality	All-Cause Mortality	CVD-specific Mortality	CHD-specific Mortality
Vessel Number
1-Vessel	1 (ref)	1 (ref)	1 (ref)	1 (ref)	1 (ref)	1 (ref)
2-Vessel	1.1 (0.9 to 1.4)	1.4 (0.9 to 1.9)	2.0 (1.1 to 3.6)	1.1 (0.9 to 1.3)	1.3 (0.9 to 1.9)	1.9 (1.1 to 3.4)
3-Vessel	1.3 (1.1 to 1.5)	1.8 (1.3 to 2.5)	2.7 (1.6 to 4.7)	1.2 (1.04 to 1.5)	1.7 (1.2 to 2.4)	2.6 (1.5 to 4.5)
4-Vessel	1.4 (1.1 to 1.7)	2.0 (1.3 to 2.8)	2.7 (1.5 to 4.9)	1.3 (1.1 to 1.6)	1.8 (1.2 to 2.6)	2.5 (1.4 to 4.5)
Index of Diffusion (Only ≥ 2 vessels)
Concentrated	1 (ref)	1 (ref)	1 (ref)	1 (ref)	1 (ref)	1 (ref)
Normal	1.04 (0.9 to 1.2)	1.2 (0.9 to 1.6)	0.9 (0.6 to 1.2)	1.02 (0.9 to 1.2)	1.2 (0.9 to 1.6)	0.9 (0.6 to 1.3)
Diffuse	1.2 (0.97 to 1.4)	1.5 (1.1 to 2.1)	1.3 (0.8 to 2.0)	1.2 (0.95 to 1.4)	1.4 (1.02 to 2.0)	1.2 (0.8 to 19)

^†Model 1 includes age (as a continuous variable), sex, study site, baseline statin use, and Agatston CAC score (continuous).

^‡Model 2 includes Model 1 + hypertension, dyslipidemia, and diabetes

^*CVD mortality includes the following: other circulatory disorder, CHD, stroke, and congestive heart failure.