Table 6.
Adjuvant chemotherapy | ||||||||
---|---|---|---|---|---|---|---|---|
Assessment | Scale | Good score | Yes | No | AUROC (SE) | |||
N | Statistic | N | Statistic | p-value | ||||
Pre-operative assessments | ||||||||
Katz IADL (% scoring 6*) | 0–6 | High | 26 | 26 (100%) | 5 | 5 (100%) | 0.50 (0.14) | 1.000 |
Fried scale score | 0–5 | Low | 27 | 1 (0–2) | 7 | 1 (0–2) | 0.52 (0.12) | 0.896 |
Lawton ADL (% scoring 8*) | 0–8 | High | 27 | 24 (89%) | 7 | 6 (86%) | 0.51 (0.12) | 1.000 |
Clinical frailty scale | 1–9 | Low | 27 | 2.3 ± 1.1 | 7 | 3.0 ± 0.8 | 0.71 (0.10) | 0.087 |
Edmonton frail scale | 0–18 | Low | 26 | 0 (0–2) | 6 | 1 (1–2) | 0.73 (0.09) | 0.064 |
Mini nutritional assessment | 0–14 | High | 27 | 10 (9–12) | 7 | 11 (7–11) | 0.59 (0.12) | 0.507 |
MoCA score | 0–30 | High | 19 | 26 (24–27) | 6 | 25 (20–26) | 0.68 (0.12) | 0.201 |
Hand grip strength | Kg | High | 20 | 31.3 ± 10.0 | 6 | 29.8 ± 11.1 | 0.55 (0.14) | 0.733 |
Short physical performance (% scoring 12*) | 0–12 | High | 22 | 17 (77%) | 6 | 2 (33%) | 0.72 (0.13) | 0.043 |
Six-minute walk test | Metres | High | 22 | 454 ± 112 | 6 | 277 ± 48 | 0.91 (0.06) | 0.001 |
Post-operative assessments | ||||||||
Hand grip strength | Kg | High | 25 | 28.2 ± 11.0 | 7 | 25.2 ± 8.2 | 0.60 (0.12) | 0.453 |
Short physical performance | 0–12 | High | 25 | 8 (6–12) | 7 | 6 (5–7) | 0.73 (0.11) | 0.060 |
Six-minute walk test | Metres | High | 23 | 243 ± 99 | 7 | 150 ± 124 | 0.79 (0.13) | 0.019 |
Patients that died post-operatively were excluded from the analysis (N = 3). Data are reported as median (interquartile range) or as mean ± standard deviation, unless stated otherwise, with p-values from Mann–Whitney U tests. Bold p-values are significant at p < 0.05
*The majority of the cohort scored the maximum number of points; hence, the proportion of cases with this score is reported to allow clearer comparison between groups; however, the p-values are based on the actual observed values
AUROC, area under the receiver operating characteristic curve; SE, standard error