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Model of progression of biomarkers over the course of AD. Aβ42, amyloid beta monomer from amino acid 1 to 42; Aβi, intermediate amyloid beta; AD, Alzheimer’s disease; CSF, cerebrospinal fluid; FDG, fluorodeoxyglucose; MCI, mild cognitive impairment; MRI, magnetic resonance imaging; PET, positron emission tomography
