Table 2.
Multivariate Cox regression with feature selection (Lasso regularization (s to z)).
| Feature | Adjusted hazard ratio (95% confidence interval) |
p value |
|---|---|---|
| Extubation (yes vs. no) | 1.46 (1.11; 1,92) | 0.007 |
| Ranked total circulatory drugs dose at WLST reference = 0 | ||
| > 0 and < 0.6 | 1.14 (0.90; 1.45) | 0.296 |
| ≥ 0.6 and < 0.9 | 1.35 (0.98; 1.85) | 0.068 |
| ≥ 0.9 | 2.19 (1.50; 3.18) | < 0.001 |
| Centre (Group 2 vs. Group 1) | 1.61 (1.24; 2.09) | < 0.001 |
| Attempted donation after circulatory death (yes vs. no) | 1.63 (1.22; 2.19) | < 0.001 |
| Glasgow Coma Scale (cont.) | 0.91 (0.86; 0.96) | < 0.001 |
| Pupillary reflex (absent vs. present) | 1.34 (1.08; 1.66) | 0.008 |
| Cough reflex (absent vs. present) | 1.23 (0.989; 1.53) | 0.063 |
| Peak inspiratory pressure [cmH2O] (> 30 vs. ≤ 30) | 1.54 (1.17; 2.03) | 0.002 |
| Mechanical ventilation mode (controlled vs. supported) | 1.37 (1.08; 1.73) | 0.01 |
| FiO2 (cont.) | 1.005 (1.0; 1.009) | 0.034 |
| Mean arterial pressure [mmHg] (cont.) | 0.986 (0.981; 0.991) | < 0.001 |
| Heart rate [bpm] (cont.) | 1.007 (1.003; 1.011) | < 0.001 |
| pH (cont.) | 0.31 (0.15; 0.36) | < 0.001 |
| Total ranked dose of opioids (cont.) | 1.41 (1.12; 1.76) | 0.003 |
| BMI (cont.) | 1.016 (1.003; 1.029) | 0.019 |
| APACHE II score (cont.) | 1.011 (0.999; 1.023) | 0.076 |