Table 1.
Demographics and comorbidities by surgical procedure of keratoplasty.
| Characteristic | Total N = 730 |
Surgical procedure of keratoplasty | p-value1 | |||
|---|---|---|---|---|---|---|
| [A] PK N = 198 |
[B] DSAEK N = 277 |
[C] nDSAEK N = 138 |
[D] DMEK N = 117 |
|||
| Number of patients, n | 567 | 165 | 228 | 123 | 108 | |
| Age [years] | ||||||
| Mean (SD) | 71.2 (10.6) | 67.2 (12.3) | 72.5 (9.8) | 73.1 (10.2) | 72.6 (8.1) | < 0.001 |
| Median [range] | 73.0 [41.0, 97.0] | 70.0 [41.0, 90.0] | 74.0 [41.0, 97.0] | 74.0 [45.0, 90.0] | 74.0 [48.0, 89.0] | |
| Sex, n (%) | ||||||
| [1] Male | 359 (49.2%) | 119 (60.1%) | 145 (52.3%) | 56 (40.6%) | 39 (33.3%) | < 0.001 |
| [2] Female | 371 (50.8%) | 79 (39.9%) | 132 (47.7%) | 82 (59.4%) | 78 (66.7%) | |
| Hypertension, n (%) | 149 (20.4%) | 32 (16.2%) | 69 (24.9%) | 36 (26.1%) | 12 (10.3%) | 0.003 |
| Diabetes mellitus, n (%) | 99 (13.6%) | 21 (10.6%) | 52 (18.8%) | 18 (13.0%) | 8 (6.8%) | 0.014 |
| Atopic dermatitis, n (%) | 11 (1.5%) | 5 (2.5%) | 6 (2.2%) | 0 (0.0%) | 0 (0.0%) | 0.192 |
| Herpetic keratitis, n (%) | 42 (5.8%) | 27 (13.6%) | 9 (3.2%) | 5 (3.6%) | 1 (0.9%) | < 0.001 |
| Glaucoma and surgery, n (%) | ||||||
| [1] No glaucoma | 514 (70.4%) | 150 (75.8%) | 158 (57.0%) | 98 (71.0%) | 108 (92.3%) | < 0.001 |
| [2] Glaucoma without surgery | 64 (8.8%) | 14 (7.1%) | 27 (9.7%) | 15 (10.9%) | 8 (6.8%) | |
| [3] Glaucoma with surgery | 152 (20.8%) | 34 (17.2%) | 92 (33.2%) | 25 (18.1%) | 1 (0.9%) | |
| Prior KP in opposite eye, n (%) | ||||||
| [1] No | 572 (78.4%) | 158 (79.8%) | 222 (80.1%) | 113 (81.9%) | 79 (67.5%) | 0.120 |
| [2] Yes | 157 (21.5%) | 39 (19.7%) | 55 (19.9%) | 25 (18.1%) | 38 (32.5%) | |
| [3] Unknown | 1 (0.1%) | 1 (0.5%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |
| Filtering bleb, n (%) | 127 (17.4%) | 25 (12.6%) | 80 (28.9%) | 22 (15.9%) | 0 (0.0%) | < 0.001 |
| Follow-up period up to last visit [days] | ||||||
| Mean (SD) | 1,559 (1,197) | 1,949 (1,446) | 1,173 (852) | 1,992 (1,399) | 1,307 (714) | < 0.001 |
| Median [range] | 1,190 [90, 5,758] | 1,490 [97, 5,758] | 948 [90, 5,632] | 1,854 [95, 5,198] | 1,123 [165, 3,856] | |
| Follow-up period up to last visit [years] | ||||||
| Mean (SD) | 4.3 (3.3) | 5.3 (4.0) | 3.2 (2.3) | 5.5 (3.8) | 3.6 (2.0) | |
| Median [range] | 3.3 [0.2, 15.8] | 4.1 [0.3, 15.8] | 2.6 [0.2, 15.4] | 5.1 [0.3, 14.2] | 3.1 [0.5, 10.6] | |
DMEK descemet membrane endothelial keratoplasty, (n)DSAEK (non-)descemet’s stripping automated endothelial keratoplasty, PK penetrating keratoplasty, SD standard deviation.
Significant values are given in bold.
1Kruskal–Wallis test for continuous variables; Chi-square test for categorical variables.