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. 2023 Feb 14;13:2635. doi: 10.1038/s41598-023-29659-w

Table 2.

Indication of keratoplasty.

Characteristic Total
N = 730
Surgical procedure of keratoplasty p-value1
[A] PK
N = 198
[B] DSAEK
N = 277
[C] nDSAEK
N = 138
[D] DMEK
N = 117
Indication, n (%)
 [01] Failed KP 172 (23.6%) 44 (22.2%) 95 (34.3%) 26 (18.8%) 7 (6.0%)  < 0.001
 [02] ALI 125 (17.1%) 4 (2.0%) 33 (11.9%) 47 (34.1%) 41 (35.0%)
 [03] PBK 82 (11.2%) 6 (3.0%) 34 (12.3%) 26 (18.8%) 16 (13.7%)
 [04] Glaucoma surgery 78 (10.7%) 14 (7.1%) 48 (17.3%) 16 (11.6%) 0 (0.0%)
 [05] Corneal opacity 48 (6.6%) 40 (20.2%) 7 (2.5%) 0 (0.0%) 1 (0.9%)
 [06] FED 48 (6.6%) 0 (0.0%) 17 (6.1%) 3 (2.2%) 28 (23.9%)
 [07] XFS 27 (3.7%) 1 (0.5%) 11 (4.0%) 6 (4.3%) 9 (7.7%)
 [08] Keratoconus 21 (2.9%) 21 (10.6%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
 [09] Perforation 17 (2.3%) 17 (8.6%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
 [10] Infection 13 (1.8%) 13 (6.6%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
 [11] CMV 12 (1.6%) 0 (0.0%) 7 (2.5%) 1 (0.7%) 4 (3.4%)
 [12] Corneal dystrophy/degeneration 11 (1.5%) 7 (3.5%) 1 (0.4%) 0 (0.0%) 3 (2.6%)
 [13] ICE 3 (0.4%) 1 (0.5%) 2 (0.7%) 0 (0.0%) 0 (0.0%)
 [14] Others 73 (10.0%) 30 (15.2%) 22 (7.9%) 13 (9.4%) 8 (6.8%)
Failed KP breakdown, n
 [1] Failed PK 67 36 14 15 2
 [2] Failed DSAEK 67 5 58 4 0
 [3] Failed nDSAEK 17 0 9 6 2
 [4] Failed DMEK 15 0 12 0 3
 [5] Failed DALK 5 3 2 0 0
 [6] Unknown 1 0 0 1 0

ALI argon laser iridotomy, CMV cytomegalovirus, DALK Deep anterior lamellar keratoplasty, DMEK Descemet membrane endothelial keratoplasty, (n)DSAEK (non-)Descemet’s stripping automated endothelial keratoplasty, FED Fuchs’ endothelial dystrophy, ICE iridocorneal endothelial syndrome, PBK pseudophakic bullous keratopathy, PK penetrating keratoplasty, XFS exfoliation syndrome.

Significant values are given in bold.

1Chi-square test.